Pure Encapsulations SAMe (S-Adenosylmethionine) 60 Capsules

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  • Pure Encapsulations SAMe (S-Adenosylmethionine) 60 Capsules
  • Pure Encapsulations SAMe (S-Adenosylmethionine) 60 Capsules label
Was: CAD $88.34
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Pure Encapsulations SAMe (S-Adenosylmethionine) 60 Capsules:

enhanced-stability form SAMe; Helps to promote healthy mood balance; Helps relieve pain due to osteoarthritis

SAMe (S-adenosylmethionine) is a metabolite present in all living cells. It functions as a donor of methyl groups in over 100 different reactions and contributes to the synthesis, activation and/or metabolism of hormones, neurotransmitters, nucleic acids, phospholipids, and proteins. Methyl groups act as a signal throughout the body, regulating genetic expression and cellular function.

SAMe also promotes healthy mood balance, as indicated in clinical studies. In a meta-analysis from controlled trials and 791 individuals, SAMe offered statistically significant support for positive mood, believed to be due to its support for neurotransmitter monoamine synthesis and function, including dopamine and serotonin. It also helps to promote healthy protein turnover and maintains healthy phospholipid methylation to support phosphatidylcholine production and cellular membrane integrity and fluidity.

It Helps supports joint flexibility and comfort in individuals with osteoarthritis as well. In a meta-analysis from 11 studies, SAMe offered statistically significant support for joint function. It is believed to relieve osteoarthritis pain by supporting proteoglycan synthesis, as well as helping to stabilize and protect the proteoglycans.


Each Capsule Contains:
SAMe (S-Adenosylmethionine)
200 mg


Non medicinal Ingredients: Ascorbyl palmitate, Calcium chloride, Calcium oxide, Cellulose, Hydroxypropyl Methylcellulose, Purified water.

Purity: Manufactured using a solvent-free manufacturing process, Made with hypoallergenic, vegan ingredients.

Suggested Adult Dose: take 2 capsules up to 3 times daily or as directed by a healthcare practitioner.

Cautions: Do not use if you are pregnant or breastfeeding. Consult a health care practitioner if symptoms persist or worsen. Consult a health care practitioner prior to use if you are taking medication such as antidepressants, hepatoxic drugs or monoamine oxidase (MAO) inhibitors. Do not take at night, as the product may cause anxiety, restlessness and insomnia. Do not use if you have been diagnosed with bipolar disorder. Some people may experience mild gastrointestinal upsets (such as stomach pain, nausea, diarrhoea, and flatulence), anxiety, restlessness, insomnia, hyperactive muscle movement, and hypomania, in which case discontinue use and consult a health care practitioner.

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