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Genestra Berberis Formula 90 Capsules

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SKU:: 2126
UPC:: 883196113224
MPN:: 7519

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Description

Description

Genestra Berberis Formula 90 Veg Capsules :

Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as dyspepsia, and as a mild laxative.

Includes goldenseal root extract, barberry root and stem extract, barberry root bark, Oregon grape root extract, and Oregon grape root

Berberis Formula is a blend of barberry, goldenseal and Oregon grape extracts that are traditionally used in Herbal Medicine to help maintain gastrointestinal health. The main bioactive ingredient in these extracts is berberine.^1,2 Recent research demonstrates that berberine inhibits bacterial attachment to the gastric mucosa.³ Berberine also mediates the transport of ions and water across intestinal epithelial cells.³ It helps maintain the balance between electrolytes and water, resulting in an anti-diarrheal effect.3 Berberine can increase the expression of the Na+; H+ exchanger and aquaporin,² which help enhance the absorption of sodium and water, respectively.^3,4Berberine also promotes proper intestinal epithelial tight junction formation, and decreases the permeability of these cells to promote appropriate gastrointestinal barrier function.⁵ During low contractile states, berberine stimulates the jejunum through the activation of muscarinic receptors, resulting in increased intestinal motility, and a mild laxative effect.^₆

Supplement Facts:

Medicinal Ingredient per dose:
Barberry (Berberis vulgaris) Root & Stem Extract(4:1)		200 mg/ DHE 800 mg
Oregon Grape (Berberis aquifolium) Root Extract (4:1)		200 mg/ DHE 800 mg
Goldenseal (Hydrastis canadensis) Root Std. Extract (10:1) (5% Hydrastine)		50 mg/ DHE 500 mg
Barberry (Berberis vulgaris) Root		25 mg
Oregon Grape (Berberis aquifolium) Root		25 mg

Non-Medicinal Ingredients: Hypromellose, cellulose, silica

Guaranteed to contain no added wheat, starch, yeast, gluten, corn, soy, salt, sugar, artifical coloring or flavoring, preservatives, dairy or animal products.

Quality Assurance Tamperresistant package. Do not use if outer seal is missing or broken. Store in a cool, dry place.

Recommended Adult Dosage (over 19 years): Take one capsule two times daily with meals or as recommended by your health care practitioner. May take up to one week to produce beneficial effects.

Risk Information:

Cautions and Warnings:

If symptoms persist or worsen, consult your health care practitioner. If you have a kidney disorder, blood pressure problems, heart or respiratory condition, consult your health care practitioner prior to use. Consumption with alcohol, other medications and/or natural health products with sedative properties is not recommended. Do not exceed the recommended dose. Discontinue use and consult a health care practitioner if the following symptoms occur: nausea, vomiting, drop in blood pressure and/or difficulty breathing.

Contra-Indications:

If you are pregnant or breastfeeding, do not use.

Known Adverse Reactions:

High dosages of berberine can depress respiration, stimulate intestinal smooth muscle and reduce bronchial constriction.

References:

1. Javadzadeh, SM, Ebrahimi, A. Sci. Agri. 2013; 1(2): 61-66.
2. Siow, YL, Sarna, L, O, K. Food Research International. 2011; 44: 2409-2417.
3. Chen, C, Yu, Z, Li, Y, Fichna, J, Storr, M. The American Journal of Chinese Medicine. 2014; 42(5): 1053-1070.
4. Zhang, Y, Wang, X, Sha, S, Liang, S, Zhao, L, Liu, L, Chai, N, Wang, H, Wu, K. BFitoterapia. 2012; 83: 1014-1022.
5. Gu, L, Li, N, Gong, J, Li, Q, Zhu, W, Li, J. The Journal of Infectious Diseases. 2011; 203: 1602-1612.
6. Chen, DP, Xiong, YJ, Lv, BC, Liu, FF, Wang, L, Tang, ZY, Lin, Y. Journal of Pharmacy and Pharmacology. 2013; 65(5): 734-744.

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