Cyto Matrix Estro Matrix 90 Veg Capsules

Cyto Matrix Estro Matrix 90 Veg Capsules:

Helps to promote healthy estrogen balance and reduce the severity and duration of symptoms associated with recurrent breast pain. Provides antioxidants that help protect against cell damage caused by free radicals.

Suboptimal liver and digestive tract function, in combination with excessive exposure to xenoestrogens, can lead to enterohepatic recirculation of estrogens and ultimately create an estrogen- dominant state with negative health implications for the body. Thankfully, a number of natural compounds have been identified to promote proper estrogen detoxification and healthy hormone metabolism.

Indole-3-carbinol (I-3-C) is naturally found in cruciferous vegetables such as broccoli and cauliflower and it is well-known for its ability to support female endocrine metabolism. I-3-C upregulates the production of 2-OHE1, the protective form while 16-OHE1contributes to proliferative effects. Research has repeatedly shown that a higher ratio of 2-OHE1 to 16-OHE1 is protective against disease and desirable for improving symptoms in estro dominant conditions. I-3-C improves this ratio of estro metabolites.

I-3-C has been shown to improve estro ratios and health outcomes in women with cervical disease. Animal studies have also found that I-3-C can prevent unhealthy cellular differentiation in breast tissue. Not only does I-3-C promote a positive endocrine metabolite ratio, but it additionally influences the expression of multiple genes, such as tumor-suppressing gene p53 and BRCA1, that collectively support the healthy differentiation of hormonally sensitive tissues.

I-3-C is naturally metabolized in the body to provide multiple active compounds, including the predominant metabolite diindolylmethane (DIM). Although debate exists regarding whether DIM or I-3-C is most beneficial as a health supplement, each compound has its advantages. I-3-C provides the body with many active metabolites, while DIM appears to be a primary metabolite with a potent detoxification activity. Both compounds are well-researched and effective treatments for the proper regulation of estrogens in the body.

D-glucarate, or glucaric acid, is another natural compound found naturally in oranges, carrots, apples and broccoli, and it promotes the detoxification of excess hormones, various toxins and carcinogens by deactivating B-glucoronidase. B-glucoronidase is an enzyme produced by colonic microflora that can ‘reactivate’ compounds that had previously been neutralized by the liver, preventing the recirculation of these toxins in the body. Animal studies have found that large doses of calcium-D-glucarate can reduce estrogen levels in the blood by up to 23% and also favorably impact lipid balance. Quite simply, calcium-D-glucarate is one of the best known natural B-glucoronidase inhibitors and the best studied form to safely deliver D-glucarate.

Finally, sulphoraphane glucosinolate (SGS) is a naturally occurring compound that, like I-3-C and DIM, is also found in broccoli and cruciferous vegetables. Numerous clinical trials support its use in promoting healthy cellular differentiation through the removal of xenobiotics and powerful induction of phase 2 detoxification enzymes in the liver. For example, SGS has been shown to reduce the carcinogenic effects of aflatoxin exposure on liver tissue. SGS also has anti-inflammatory actions through the inhibition of nuclear factor kappaB (NFkB), prostaglandin E2 and tumor necrosis factor-alpha (TNF-a), it can reduce estrogen receptor expression in breast tissue and it has antimicrobial activity against pathogens such as H. pylori, S. pyogenes and S. aureus.

Estro Matrix provides evidence-based dosages of synergistic ingredients to offer targeted and ongoing endocrine support through the proper metabolism of estrogens.

Ingredients:

Non Medicinal Ingredients:  Vegetable-grade magnesium stearate, microcrystalline cellulose. Capsule: hypromellose.

Suggested Dose: Adults - Take 1 softgel per day or as directed by a healthcare professional.

Cautions: Do not use if safety seal is broken. Consult a healthcare professional prior to use, especially if you are taking other medications or natural health products and to exclude the diagnosis of a serious cause of hormonal imbalance. Consult a healthcare professional if you are attempting to conceive, have a liver disorder or symptoms of low estrogen (such as joint pain, mood changes, changes in libido, hot flashes, night sweats, vaginal dryness or irregular menstruations) or if you develop liver-related symptoms (e.g. yellowing of the eyes and/or skin, dark urine, abdominal pain, jaundice) or symptoms of low estrogen. If recurrent breast pain persists or worsen, consult a healthcare professional. Do not use if you are pregnant or breastfeeding.