Biotics Research Berberine HCl 90 Capsules
Biotics Research Berberine HCl 90 Capsules:
Helps to maintain/support cardiovascular health. Provides support for healthy glucose metabolism. Provides support for healthy lipid metabolism. Helps support healthy cholesterol levels (serum triglyceride, total, and LDL).
Anti-microbial (fungus, bacteria, yeasts, patasites)
Berberine has demonstrated significant activity against bacteria, yeasts, fungus and parasites. Berberine also has been shown to be supportive of healthy blood sugar levels as well as supporting normal blood lipid levels.
Berberine extracts and decoctions have demonstrated significant antimicrobial activity against a variety of organisms including bacteria, viruses, fungi, protozoans, helminths, and chlamydia. Thus, not surprisingly the current predominant clinical use of berberine includes bacterial diarrhea, intestinal parasite infections, and ocular trachoma infections. The Textbook of Natural Medicine indicates its pharmacological activities as antibiotic, immunostimulatory, anticonvulsant, sedative, hypotensive, uterotonic, cholerectic and carminative.
In addition to these actions, it has also demonstrated benefits in the regulation of blood sugar, in decreasing lipids, in the modulation of blood pressure and recently has been designated as a beneficial component in the management of Alzheimers disease.
As an antibacterial compound, berberine has demonstrated effectiveness against a broad spectrum of bacteria, yeasts, fungus and parasites. Bacterial susceptibility to Berberine includes Staphylococcus aureus, Streptococcus pyogenes, Eschericha coli, Shigella boydii, Vibrio cholerae, and Mycobacterium tuberculosis.
Yeasts and fungal susceptibility includes Candida albicans, Candida tropicalis, Trichophyton mentagrophytes, Microsporum gypseum, Cryptococcus neoformans, and Sporotrichum schenkii; while parasitic susceptibility, includes Entamoeba histolytica, and Giardia lamblia. Its mechanism of action is thought to result in part due its characteristic structure, that of a planar cationic molecule. This structural arrangement enables it to intercalate the DNA structure, similar in fashion to the mechanism of ethidium bromide.
|Medicinal Ingredients per capsule:|
|Berberine Hydrochloride||500 mg|
|Non-medicinal ingredients: Cellulose, capsule shell (gelatin and water) magnesium stearate (vegetable source).|
Non-medicinal ingredients: Cellulose, capsule shell (gelatin and water) magnesium stearate (vegetable source).
Suggested Directions: One (1) capsule each day or as recommended by your health care practitioner.
Safety: Not recommended for children, pregnant or lactating women.
Cautions and Warnings: Consult a health care practitioner prior to use if you are taking other medications or natural health products. Consult a health care practitioner prior to use if you have hypoglycemia or hypotension. Consult a health care practitioner prior to use if you have a liver or kidney disorder, cardiovascular disease, diabetes or a blood disorder. If you have gall stones, consult a health care practitioner prior to use.
Contra-Indications: Do not use if you are pregnant or breastfeeding.
Known Adverse Reactions: Some people may experience skin irritation, facial flushing and slowed heart rate. May cause gastrointestinal discomfort such as constipation, vomiting, abdominal pain or diarrhea in which case discontinue use and consult a health care practitioner.
1. Berberine. Altern Med Rev. 2000;5(2):175-177.
2. Jennings BR, Ridler PJ. Interaction of chromosomal stains with DNA. Anelectrofluorescence study. Biophys Struct Mech. 1983;10(1-2):71-9.
3. Yin J, Xinga H, Yeb J. Efficacy of berberine in patients with type 2 diabetesmellitus. Metabolism Clinical and Experimental. 2008 57:712–717.
4. Liua L-Z, Cheunga SCK, Lana L-L, Hoa SKS, Xub H-X, Chana JCN, TongPCY. Berberine modulates glucose regulating hormone signaling transduction in resistant cells. Molecular and Cellular Endocrinology. April 2010 317(1-2): 148–153.
5. Kong Weijia, et al. Berberine is a novel cholesterol-lowering drug workingthrough a unique mechanism distinct from statins. Nature Medicine. 200410(12):1344-1351.