Aor Inositol 90 Veg Capsules

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Description

Aor Inositol 90 Veg Capsules:  

Protect Your Cells.

  • A key component for healthy cells
  • Supports healthy cell growth and formation
  • Available in capsule and powder form for varied dose and therapeutic effectve

Inositol Caps contain myo-inositol, a B-vitamin-like simple polyol. Inositol forms the basis for phosphatidylinositol, a key cellular phospholipid. Importantly, recent research supports a role for inositol in cellular defense and normal cell growth and differentiation for the maintenance of good health, especially in combination with inositol hexaphosphate (IP6).

Inositol (or myo-inositol) is a B-vitamin-like molecule often used to help regulate blood sugar, manage polycystic ovarian syndrome (PCOS), and manage mood disorders such as anxiety. Inositol is a precursor to phosphatidylinositol, which is central to the phosphoinositide cycle. This cycle is essential to multiple brain signaling systems, delivering messages from a variety of hormones and neurotransmitters (brain messenger-molecules) from receptors on the nerve cell membrane to the inside of the cell. Essentially, inositol helps to improve the sensitivity of various receptors, which in turn helps to balance mood and blood sugar in cases of PCOS.

Research suggests that high doses of inositol can address the symptoms of behavioural and compulsive disorders, particularly those related to mood imbalances and worrying. Signaling systems dependent on the phosphoinositide system include neurotransmitters, which are key targets for antidepressant drugs. Recent research also supports a role for lower doses of inositol in cellular defense and normal cell growth and differentiation, especially in combination with I-P-6 (inositol hexaphosphate or phytate). Those suffering with poor regulation of blood sugar, polycystic ovarian syndrome (PCOS), or mood disorders such as anxiety may benefit from Inositol. It is also useful for people concerned with healthy cellular growth and differentiation.

Medicinal Ingredients Per 1 Capsule:
Myo-Inositol
500 mg
Non-medicinal ingredients: hypromellose.

 Find Aor Supplements at healthpalace.ca

AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish.

Suggested Use:
Take 1 heaping tablespoon twice daily with food, or as directed by a qualified health care practitioner.

Source for powder and capsules:
Oryza sativa (rice bran)

Pregnancy / Nursing for powder and capsules:
Consult a health care practitioner prior to use if pregnant or breastfeeding.

Cautions:
For adult use only.  Consult a health care practitioner prior to use if pregnant or breastfeeding. Consult a health care practitioner for use beyond duration of 3 weeks. May cause side effects such as nausea, tiredness, headaches and dizziness. 

Main Applications:

  • Healthy cellular growth
  • Mood

Research:

Depression
In one of the first clinical trials, researchers assembled 39 people with major depression or bipolar depression, who quit taking their antidepressant medications three days to a week before the trial began. For the next four weeks, sufferers took either twelve grams of inositol powder a day (two teaspoons, twice daily, in juice) or a placebo powder (glucose).

Hamilton depression Rating Scale (HAM-D) scores fell during the first two weeks, people taking inositol powder experienced an additional 20.5% drop in their depression scores by the end of the trial. Plus, inositol was not associated with manic episodes in the victims of bipolar depression - an important result, since many treatments for this disorder push its victims into the opposite pole, with disastrous consequences.

Bipolar Depression
Buoyed by the success of patients with bipolar affective disorder depression who had taken inositol in the first trial, scientists next initiated a trial using only victims of this specific disease. In this trial, 24 men and women suffering with bipolar depression were randomly placed into groups supplementing with either 12 grams of inositol powder or an equal amount of glucose powder as a placebo for six weeks. All patients kept up their standard medications throughout the trial.

At the end of the trial, half of the people taking the inositol powder supplement enjoyed a 50% or greater relief of their depression as measured on the HAM-D; likewise on the Clinical Global Improvement (CGI) scale, the same inositol supplementers were seen to be "much" or "very much" improved. By contrast. Similarly, twice as many people supplementing with the inositol powder improved by 50% or more on the Montgomery-Asberg Depression Rating Scale (MADRS) as people stuck with the placebo.

The effects the physicians saw in their patients lives left them confident that the power of inositol in victims of bipolar depression is real.

Eating Disorders
Twenty-four bulimic or binge eating patients took part in a double-blind, placebo-controlled crossover trial in which, after an initial run-in period, they took either 18 grams of inositol powder or a sugar placebo for six weeks each. They then switched over to taking the substance, which they had not taken in the previous period, again for six weeks. No one knew which sweet powder a given person was taking at a given time.

When the "blinds" came off at the end of the study, it was revealed that these eating disorder victims experienced a 45% alleviation in their Visual Analog Scale of severity of binge eating (VAS-B) scores, along with a 30% improvement on their CGI scores, a 24% better Eating Disorder Inventory (EDI) result, and a 28% healthier Eating Attitude Test (EAT) result while supplementing with inositol powder.

Panic Disorder
In yet another study, 21 people with panic disorder who wanted to escape the side effects of their drug therapies completed a double-blind trial of inositol powder. All stopped taking their standard medications one week before starting the study; after a one week run-in period, the participants supplemented with one of two sweet powders - either inositol or a placebo powder (6 grams of glucose or mannitol, twice daily) - for four weeks.

Every outcome was improved while people were supplementing with inositol powder. Inositol users suffered over 40% fewer panic attacks per week than they did when only taking a sugar. Their panic scores were only a third as high as they were during their time on a placebo, and their phobia scores were more than a third lower. And while the results did not cross the threshold of statistical significance, raw HAM-D and HAM-S scores also fell more in the inositol supplementation period than when they were swallowing the powdered sweeteners. Clearly, inositol powder lifted of much of the desperate burden of nameless anxiety from the shoulders people who took it.

In a second trial, researchers pitted inositol head-to-head against fluvoxamine (Luvox®) in a double-blind, placebo-controlled, random-order crossover study. For one month, twenty victims of panic disorder took either a dummy Luvox® tablet and real inositol powder (18 grams), or real Luvox® and powdered sugar as a stand-in for inositol; then, they were switched to the opposite combination for a second month.

It was exciting enough when the study revealed that by most criteria, people got just as much relief from panic by using inositol supplements as they did from taking the drug: HAM-A, phobia, and CGI scores all improved by about the same amount in both groups. This alone is enough to merit the attention of panic disorder victims and their physicians - especially when you consider how much more often drug users traded symptomatic relief for side effects such as nausea (twice as common) and tiredness (nine times more likely).

But in fact, the study revealed that inositol is actually more effective than fluvoxamine in reducing the number of panic attacks suffered, cutting weekly attacks by 57% while the drug only reduced them by 41%!

Obsessive-Compulsive Disorder (OCD)
Inositol powder has also been documented to relieve the maddening fixations of OCD. In a double-blind, placebo-controlled crossover study, thirteen obsessive-compulsive men and women completed a cycle of taking 18 grams of either inositol powder or a sugar placebo each day for six weeks, followed using the other treatment for the next six weeks.

Even on a preliminary analysis, resistant patients experienced 12.5% greater relief of obsessive symptoms while taking inositol powder, as measured on the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS),However looking at "mixed" obsessive-compulse patients, the improvement experienced from taking inositol powder was nearly double.

References:

  1. Gelber D, Levine J, Belmaker RH. Effect of inositol on bulimia nervosa and binge eating. Int J Eat Disord. 2001 Apr; 29(3): 345-8.Levine J. Controlled trials of inositol in psychiatry. Eur Neuropsychopharmacol. 1997 May; 7(2): 147-55.
  2. Levine J, Barak Y, Gonzalves M, Szor H, Elizur A, Kofman O, Belmaker RH. Double-blind, controlled trial of inositol treatment of depression. Am J Psychiatry. 1995 May; 152(5): 792-4.Levine J. Controlled trials of inositol in psychiatry. Eur Neuropsychopharmacol. 1997 May; 7(2): 147-55.
  3. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol. 2001 Jun; 21(3): 335-9.
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