Aor Hydroxy B12 - 60 Lozenges

• Hydroxocobalamin is a unique form of B12
• Required for methylation cycles
• Lozenges sweetened with xylitol

Hydroxocobalamin is a form of vitamin B12 that helps prevent a B12 deficiency, helps the body metabolize carbohydrates, proteins and fats, helps form red blood cells and is a factor in the maintenance of good health.

Hydroxy B12 is hydroxocobalamin delivered in lozenge format. Cyanocobalamin, the most common form of supplemental B12, must be converted first into hydroxocobalamin, and then into adenosylcobalamin. Adenosylcobalamin may also be converted into methylcobalamin, the other active coenzyme form. Taking hydroxocobalamin allows the body to skip a step in this conversion process, and the lozenge delivery allows for faster absorption. 

Scientists have identified B12 deficiencies as risk factors for a multitude of conditions, including neuropathy, neurodegenerative diseases, anemia, cardiovascular problems and mood imbalances, among others. Hydroxocobalamin also has the unique ability to help the body to rid itself of cyanide, both by reacting with the toxin to form cyanocobalamin (which can then be excreted) and by enhancing the detoxification of cyanide through its conversion into the less toxic thiocyanate.

Hydroxy B12 provides an active and well-absorbed form of B12 for people looking to treat or prevent deficiency and anemia in an easy to consume lozenge. It has the additional benefit of helping the body eliminate toxic cyanide. B12 supplements in general are especially important for vegetarians and to help prevent pernicious anemia.

Research:

Homocysteine Reduction for Cognitive Function In a single-blind, placebo controlled study, it investigated the effects of a treatment of hydroxocobalamin on 16 healthy elderly subjects with low plasma Cbl concentration, but who were without cerebral and cognitive abnormalities. After one month of treatment with a placebo and then five months of treatment with intramuscular injections of hydroxocobalamin, it was determined that after supplementation with the cobalamin, plasma Cbl concentrations increased, and plasma MMA and tHcy concentrations decreased. Before and after the measurements were taken for levels of plasma cobalamin, total homocysteine (tHcy), methylmalonic acid (MMA), quantitative electroencephalograph (qEEG), and psychometric tests were taken. Improvements were observed on Verbal Word Learning Test and Verbal Fluency; electrographic signs also indicated improved cerebral function and improved cognitive function. These improvements were related to a reduction of plasma tHcy concentration.

Cyanide Exposure Another study investigated the effects of administering hydroxocobalamin to firefighters who have suffered from hydrogen cyanide smoke inhalation, in order to determine if an early intervention with the administration of vitamin b12 coenzyme could have a positive effect. 161 firefighters who were suspected or confirmed to have hydrogen cyanide poisoning were studied in a multicenter retrospective case review from the Emergency Medical Assistance Unit.

References:

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