Aor Maxmethyl 90 Veg Capsules
Aor Maxmethyl 90 Veg Capsules:
- Decreases dangerous levels of homocysteine
- Lowers the risk of cardiovascular disease
- Protects against damaged blood vessels
- Slows the aging process
MaxMethyl provides nutrients that help in tissue formation, the formation of red blood cells, the metabolism of carbohydrates, fats and proteins and which are factors in the maintenance of good health.
Methylation is a key process that is essential for the function of every cell in the body, keeping aging and disease at bay. Methylation reduces homocysteine, a toxic amino acid that dramatically increases the risk of heart disease, cancer, bone loss, joint degradation, mood imbalances and cognitive decline.
MaxMethyl contains all the cofactors and methyl donors needed to promote methylation and convert homocysteine into useful amino acids: vitamin B6, vitamin B12, folate and trimethylglycine (TMG). This combination of nutrients was shown to significantly reduce homocysteine levels after just 6 weeks of supplementation. TMG alone can reduce homocysteine plasma levels by as much as 30%. Additionally, B vitamins, specifically B6, B12 and folate, have been shown to reduce the risk of stroke due to their ability to reduce homocysteine.
Recently it was discovered that a large portion of the population has a mutation of the gene MTHFR, which prevents them from converting folate into its usable form, L-5-MTHF. This leads to folate deficiency and decreased methylation, resulting in high homocysteine levels. The folate used in MaxMethyl is in the form of L-5-MTHF, which makes it an ideal supplement for those with the MTHFR mutation.
Most people do not get enough of the specific nutrients that support methylation in their diets. MaxMethyl is an excellent supplement for aging in general, for those who know they have high homocysteine levels, and those looking for support against age-related degenerative conditions of the bones, joints, nerves and cognitive function.
|Medicinal ingredients Per 1 Capsule:|
|Trimethylglycine (betaine anhydrous)||500 mg|
|Folic acid (calcium L-5-MTHF)||267 mcg|
|Vitamin B6 (Pyridoxal-5'-phosphate)||17 mg|
|Vitamin B12 (Methylcobalamin)||216 mcg|
Find Aor Supplements at healthpalace.ca
Non medicinal ingredients: Capsule : hypromellose.
AOR Guarantees: that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, dairy, soy, eggs, fish, shellfish or any animal by product.
Adult Dosage: Take 1 capsule three times per day with or without food, or as directed by a qualified health care practitioner.
Cautions: Consult a health care practitioner prior to use if you have liver or cardiovascular disease.
Pregnancy/Nursing: Consult a health care practitioner prior to use
- Cellular health
- Cardiovascular health
- Healthy blood pressure
Protect yourself against elevated homocysteine levels
Homocysteine is a toxic amino acid. It is naturally produced in the body as a byproduct of several metabolic pathways, such as the metabolism of the amino acid methionine to produce essential nucleic acids, fats and highenergy bonds.
When methionine loses a methyl group, homocysteine is produced. If homocysteine levels increase, blood vessels are damaged and collagen formation is impeded. There are two pathways in the human body that can lead to the elimination of homocysteine: it can be methylated to methionine or condensed into cysteine. The former process requires folate and vitamin B12, while the latter is vitamin B6 dependant.
Why is Homocysteine Harmful?
Elevated blood levels of homocysteine (Hyperhomocysteinemia) have been associated with higher incidences of coronary artery disease and increased risk of mortality from cardiovascular diseases. Hyperhomocysteinemia is an independent factor for peripheral vascular, cerebrovascular and coronary heart disease. High homocysteine levels have a variety of injurious effects and are thought to damage blood vessel walls and lead to cardiovascular complications. Impairment in the conversion of homocysteine to cysteine might also lead to higher blood cholesterol levels because cysteine is required for the metabolism of cholesterol. It is also possible that the amino acid affects blood coagulation.
What causes elevated homocysteine levels?
Elevations can arise from genetic defects, or from poor consumption of nutritional factors involved in homocysteine metabolism, particularly vitamins B12, B6 and folic acid. Insufficient intake of folate, vitamin B12 and B6 are common in the elderly. However, even young, healthy adults who exercise have been found to have elevated levels of homocysteine.
- A study of over 1000 people showed that as dietary folate intake decreases, homocysteine level, narrowing of arteries, heart attacks and death due to cardiac disease increase.
- It is estimated that over 40% of the population is not consuming enough folate to keep homocysteine levels low. Hyperhomocysteinemia is believed to cause 60% of peripheral vascular disease.
- The Physician’s Health Study showed that men with higher homocysteine levels had a threefold risk of coronary events.
- Elevated homocysteine levels lead to structural defects in collagen and may play a role in osteoporosis. In vitro studies have demonstrated that homocysteine increases the activity of bone
- breaking cells, leading to bone resorption.
- Folic acid supplementation reduces homocysteine levels even if the individual is not folate deficient. Simple supplementation can reduce mild homocysteine elevation in virtually all cases.
- Folic acid supplementation is more effective than dietary folate at lowering homocysteine levels.
The ingredient combination included in AOR’s MaxMethyl was tested in a randomized, doubleblind, controlled study from the University of East London. Participants who took this combination had a significant decrease in their homocysteine levels regardless of their initial levels. Those whose initial levels of homocysteine were high enough to put them in the “at
risk” category experienced a dramatic homocysteine drop, indicating that these participants reduced their risk of cardiovascular disease in only 6 weeks of supplementation.
How can homocysteine levels be reduced?
The enzymes that metabolize homocysteine into methionine and cysteine use folate, vitamin B12, and vitamin B6 as cofactors. Trimethylglycine is a methyl group donor and has been shown to reduce plasma homocysteine levels by as much as 30%! Trimethylglycine is the most effective homocysteine lowering substance known. AOR’s MaxMethyl has been formulated to include the cofactors and methyl donors necessary for the methylation of homocysteine into other harmless amino acids, and is therefore an effective supplement for the support of cardiovascular health.
MaxMethyl is formulated to include all the cofactors and methyl donors needed to convert homocysteine into useful amino acids, thereby helping to reduce the risk of heart disease.
- Cashman KD. Homocysteine and osteoporotic fracture risk: a potential role for B vitamins. Nutr Rev. 2005 Jan;63(1):2936.
- Herrmann M, Widmann T, Herrmann W. Homocysteine – a newly recognised risk factor for osteoporosis. Clin Chem Lab Med. 2005;43(10):11117.
- Jellin JM, Gregory P, Batz F, Hitchens K, et al. Pharmacist’s Letter/Prescriber’s Letter Natural Medicines ComprehensiveDatabase. 3rd ed. Stockton, CA: Therapeutic Research Faculty; 2000
- Sato Y, Honda Y, Iwamoto J, Kanoko T, Satoh K. Homocysteine as a predictive factor for hip fracture in stroke patients.Bone. 2005 Apr;36(4):7216.
- Shils M. E., Olson J.A., Shike M., Ross A. C., Modern Nutrition in Health and Disease, 1998, 9th Edition, Baltimore,Lippincott Williams & Wilkins
- Verhoef P, de Groot LC. Dietary determinants of plasma homocysteine concentrations. Semin Vasc Med. 2005 May;5(2):11023. Review.