Aor I 3 C 60 Veg Capsules

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1080
UPC:
624917042504
Retail Price: $39.94
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Description

Aor I 3 C 60 Veg Capsules:

Protection from Estrogen Related Diseases.

  • A phytonutrient found in broccoli
  • Reduces the formation of harmful estrogens
  • An effective dose of I3C per capsule

I-3-C helps to promote healthy estrogen metabolism and balance.

Indole-3-carbinol (I-3-C) is a phytonutrient found in Brassica vegetables, like broccoli and cabbage. I-3-C is one of the key health-promoting ingredients in these foods. Though converted to DIM (3,3’-diindolylmethane) in the body, many studies have had phenomenal success using I-3-C as a supplement. Studies have revealed that by shifting the balance of metabolic enzymes that process estrogens, I-3-C reduces the formation of "bad" estrogens and increases the formation of "good" estrogens. Human studies in women taking I-3-C have shown a favourable shift in estrogen metabolism, and I-3-C has been shown to be protective against estrogen dominance in women. Estrogen dominance has been linked to fibroids, breast tenderness, premenstrual syndrome, endometriosis and other women’s health concerns.

Women who are concerned with safer estrogen metabolism, who have a family history or increased risk of estrogen-dependent cancers, or those that have a higher ratio of bad to good estrogens can benefit from this product. I-3-C may also be a beneficial supplement for those who want to reap some of the benefits of cruciferous vegetables like broccoli but have difficulty eating it raw. Overall, I-3-C is benefical for estrogen dominant conditions such as fibroids, breast tenderness, premenstrual syndrome and endometriosis.

Medicinal Ingredients per 1 Capsule:
Indole-3-Carbinol (I3C)
200 mg
Non-medicinal ingredients: microcrystalline cellulose.
Softgel: hypromellose.

Find Aor Supplements at healthpalace.ca 

AOR guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish, or any animal byproduct.

Suggested Use:

Take 1 capsule one to two times a day with or without food, or as directed by a qualified health care practitioner. 

Cautions :

Consult a health care practitioner prior to use to exclude the diagnosis of a serious cause of hormonal imbalance, if you are taking any medications or natural health products, if you are attempting to conceive, if you have a liver disorder, or symptoms of low estrogen (such as joint pain, mood changes, changes in libido, hot flashes, night sweats, vaginal dryness or irregular menstruations). Discontinue use and consult a health care practitioner if you develop liver-related symptoms (e.g. abdominal pain, jaundice) or symptoms of low estrogen. Do not use if you are pregnant or breastfeeding.

Pregnancy/Breastfeeding :

Do not use

Source:

Pharmaceutical synthesis from indole

Main Applications:

  • Estrogen metabolism
  • Women's health

References:

  1. Bell MC, Crowley-Nowick P, Bradlow HL, Sepkovic DW, Schmidt-Grimminger D, Howell P, Mayeaux EJ, Tucker A, Turbat-Herrera EA, Mathis JM. "Placebo-controlled trial of indole-3-carbinol in the treatment of CIN." Gynecol Oncol. 2000 Aug; 78(2): 123-9.
  2. Bradlow HL, Telang NT, Sepkovic DW, Osborne MP. "2-hydroxyestrone: the 'good' estrogen." J Endocrinol. 1996 Sep; 150 Suppl: S259-65. Bradlow HL, Michnovicz JJ, Halper M, Miller DG, Wong GY, Osborne MP. "Long-term responses of women to indole-3-carbinol or a high fiber diet." Cancer Epidemiol Biomarkers Prev. 1994 Oct-Nov; 3(7): 591-5.
  3. Chen I, McDougal A, Wang F, Safe S. "Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane." Carcinogenesis. 1998 Sep; 19(9): 1631-9. Jellinck PH, Forkert PG, Riddick DS, Okey AB, Michnovicz JJ, Bradlow HL. "Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation." Biochem Pharmacol. 1993 Mar 9; 45(5): 1129-36.
  4. Michnovicz JJ. "Increased estrogen 2-hydroxylation in obese women using oral indole-3-carbinol." Int J Obes Relat Metab Disord. 1998 Mar; 22(3): 227-9.
  5. Michnovicz JJ, Adlercreutz H, Bradlow HL. "Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans." J Natl Cancer Inst. 1997 May 21; 89(10): 718-23.
  6. Michnovicz JJ, Bradlow HL. "Altered estrogen metabolism and excretion in humans following consumption of indole-3-carbinol." Nutr Cancer. 1991; 16(1): 59-66.
  7. Riby JE, Chang GH, Firestone GL, Bjeldanes LF. "Ligand-independent activation of estrogen receptor function by 3, 3\'-diindolylmethane in human breast cancer cells." Biochem Pharmacol. 2000 Jul 15; 60(2): 167-77.
  8. Sanderson JT, Slobbe L, Lansbergen GW, Safe S, van den Berg M. "2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially inducecytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells." Toxicol Sci. 2001 May; 61(1): 40-8.
  9. Taioli E, Bradlow HL, Garbers SV, Sepkovic DW, Osborne MP, Trachman J, Ganguly S, Garte SJ. "Role of estradiol metabolism and CYP1A1 polymorphisms in breast cancer risk." Cancer Detect Prev. 1999; 23(3): 232-7.
  10. Wong GY, Bradlow L, Sepkovic D, Mehl S, Mailman J, Osborne MP. "Dose-ranging study of indole-3-carbinol for breast cancer prevention." J Cell Biochem Suppl. 1997; 28-29:111-6.

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