Aor Urica 90 Veg Capsules
Aor Urica 90 Veg Capsules:
Helps Relieve Gout Symptoms.
- Reduces the frequency and severity of gout attacks
- Increases excretion of uric acid from the body
- Limits production of uric acid crystals
- Unique plant based formula
Urica is a source of antioxidants for the maintenance of good health.
Gout, a form of arthritis, develops from high uric acid levels in the blood which results in the formation of crystals that are deposited in the cartilage. This leads to extremely painful attacks involving inflammation and swelling of the joints, usually the big toe. Find Aor Supplements at healthpalace.ca
Urica is designed to reduce uric acid levels in the body, thereby reducing the frequency and severity of gout attacks. This formula may also benefit those with high uric acid levels or compromised kidney function. Urica combines a high dose of morin-rich mulberry extract with supportive doses of resveratrol and grape seed extract. Morin acts on the kidneys to promote the excretion of uric acid from the body, and also helps to reduce its production by inhibiting the enzyme xanthine oxidase, which converts certain compounds into uric acid. Polyphenols from resveratrol and grape seed extract also act on the kidneys and reduce xanthine oxidase activity.
AOR’s unique formula for healthy uric acid metabolism combines ingredients with a history of traditional use that are also backed by modern research.
|Medicinal Ingredients Per 3 Capsules|
|Grape Seed Extract (Standardized to 85% oligomeric proanthocyanidins)||50mg|
|Non-medicinal ingredients: microcrystalline cellulose. Capsule: hypromellose.|
AOR guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish or any animal byproduct.
(Adult): Take 1 capsule three times daily with/without food, or as directed by a qualified health care practitioner.
Do not use if pregnant or breastfeeding. Consult a health care practitioner for use beyond 6 weeks. Consume with at least one liter of water throughout the day.
Natural botanical extracts
- Elevated uric acid levels
Gout, also referred to as metabolic arthritis or acute inflammatory monoarthritis, is caused by an abnormal build-up of uric acid in the blood – uric acid being a metabolic by-product of purine metabolism. Purines are natural substances found in many foods, and particularly in high protein foods like organ meats and fish like mackerel and sardines. Excessive blood levels of uric acid then lead to acute inflammation of the joints. ’Classic Gout’ usually targets the joints of the big toe and other joints within the legs and feet and can affect people of all ages. However, another type of gout – called ‘Atypical Gout’ – can affect any joint in either the arms or legs and is observed predominantly in the elderly. Both types of gout are characterized by excruciating pain and swelling. In many typical cases of gout, patients are overweight, predisposed to Type II diabetes and hypertension, and are at a higher risk of cardiovascular disease. Gout is disproportionately found in societies whose diets include large amounts of protein, fat and alcohol. Since a fundamental facet of gout is the metabolism of protein, the areas of kidney, bladder and urinary tract health are primary targets for treatment.
Natural Treatment Options
Mulberry has been used for centuries in Chinese medicine to help reduce the symptoms of gout. Recent research has shown that the key to mulberry’s anti-gout actions may be a unique phytochemical called Morin. Morin is a naturally-occurring flavone found in the twigs of White Mulberry. The precise mechanism of action for morin appears to be two-fold and effectively synergistic. Firstly, it acts on the kidneys to inhibit uric acid reabsorption and thus promote the excretion of uric acid from the body. Secondly, it inhibits the enzyme xanthine oxidase, which is responsible for breakdown of purines into uric acid.
Polyphenols: Grape Seed Extract and Resveratrol
Polyphenols can also play a role in the prevention of kidney stones and help support the urinary system. Resveratrol, an exceptionally potent compound of this class, may inhibit xanthine oxidase activity, while grape seed extract may reduce xanthine oxidase and acts as an antioxidant since oxidative stress is proposed to be involved in gout.
Animal studies have revealed that morin effectively inhibits the uptake of urate and to lower uric acid levels in rats. In-vitro studies have also demonstrated an anti-atherosclerosis potential on the part of morin.
Grape Seed Extract and Resveratrol
Resveratrol has been shown in-vitro to be capable of directly inhibiting xanthine oxidase activity. Polyphenols found in grape seed extract, have been shown, in-vitro, to cause a reduction in xanthine oxidase (XO) and xanthine-induced intracellular reactive oxygen species (ROS) accumulation. Researchers at the University of Hong Kong have identified ROS as being an important contributing factor in gouty arthritis. In animal models of gout (chickens), grape seed extracts have been shown to be highly effective at reducing serum uric acid levels. Find Aor Supplements at healthpalace.ca
- Du Y, et al. Grape seed polyphenols protect cardiac cells from apoptosis via induction of endogenous antioxidant enzymes. J Agric Food Chem. 2007 Mar 7;55(5):1695-701.
- Jia Z, et al. EPR studies on the superoxide-scavenging capacity of the nutraceutical resveratrol. Mol Cell Biochem. 2008 Jun;313(1-2):187-94.
- Sonlimar M and Sarmalina S. Effect of Grape (Vitis vinifera L.) Seed on Reducing Serum Uric Acid Level in Gout-Animals Model. Majalah Kesehatan PharmaMedika, 2010 Vol.2, No.1: 106-109.
- Yu Z, et al. Morin (3,5,7,2′,4′-pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURAT1) expressed in human embryonic kidney cells. Drug Metab Dispos. 2007 Jun;35(6):981-6.
- Yu Z, et al. The dual actions of morin (3,5,7,2′,4′-pentahydroxyflavone) as a hypouricemic agent: uricosuric effect and xanthine oxidase inhibitory activity. J Pharmacol Exp Ther. 2006 Jan;316(1):169-75.
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