Aor Ribogen Mg 263 Grams Powder

Cautions :

Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Ensure to adequately hydrate before, during, and after exercise.

D-Ribose and Cardiovascular Ischemia

The effectiveness of D-ribose has been demonstrated in the gold standard of scientific study; double-blind, placebo-controlled human trials. In one study of 20 men (aged 45 to 69) with severe documented coronary artery disease (CAD) and a history of angina induced by normal daily activities, 60 grams of D-ribose (in four doses of 15 grams each) were tested against a placebo. Treated subjects exhibited improvement as measured electrocardiographically, and time to onset of moderate angina (during exercise testing) increased significantly in the ribose-treated subjects. The authors concluded: “In patients with CAD, administration of ribose by mouth for three days improved the heart’s tolerance to ischemia. The presumed effects on cardiac energy metabolism offer new possibilities for adjunctive medical treatment of myocardial ischemia.” In another study involving 15 patients with coronary heart disease and congestive heart failure, it was found that 15 grams of D-ribose daily for three weeks resulted in improved diastolic heart function as well as increased scores in physical function and quality of life. Find Aor Supplements at healthpalace.ca

D-Ribose and Fibromyalgia/Chronic Fatigue Syndrome

Fybromyalgia (FMS) and Chronic Fatigue Syndrome (CFS) are debilitating conditions that have been diagnosed with increasing frequency, especially since the late 1980′s. The aforementioned role of D-ribose in the composition and generation of ATP has led to the hypothesis that it may be of assistance to patients suffering from these conditions. Scientists put this hypothesis to the test in 2006 when 41 patients diagnosed with FMS and/or CFS were given 15 grams of D-ribose daily for 19 days. The results were that 66% of the patients experienced ‘significant improvement’ in all five categories of a standardized Visual Analogue Scale questionnaire (VAS): energy; sleep; mental clarity; pain intensity; and well-being. The patients experienced an average increase of 45% in energy and 30% in well-being.

D-Ribose and Exercise

D-ribose also has benefits for healthy people who are in need of extra energy. A double blind, placebo-controlled trial observed the effects of supplemental ribose on body composition and exercise performance. 20 healthy, young male recreational bodybuilders aged 18-35 were given 10g/day D-ribose (5g before and after training) for 4 weeks. Training involved participation in a heavy-resistance program designed to increase skeletal muscle mass. There was a significant increase in the total work performed and in 1-RM bench press strength at the end of the study compared to the beginning in the D-ribose group. These changes were not seen in the placebo group, leading researchers to conclude that the supplementation contributed to increases in muscular strength and exercise performance.

D-ribose is extremely well-tolerated in human trials, and its fundamental role in the make-up and synthesis of ATP continues to attract interest from the scientific community for the study of an increasing number of health conditions affected by energy metabolism. Find Aor Supplements at healthpalace.ca

References:

1. Gammermen DV, Falk D and Antonio J. The effects of four weeks of ribose supplementation on body composition and exercise performance in healthy, young, male recreational bodybuilders: a double-blind, placebo-controlled trial. Current Therapeutic Research 2002. 63(8):486-495.
2. Omran H, et al. D-Ribose improves diastolic function and quality of life in congestive heart failure patients: a prospective feasibility study. Eur J Heart Fail. 2003 Oct;5(5):615-9.
3. Priml W, von Arnim T, Stablein A, et al. Effects of ribose on exercise-induced ischaemia in stable coronary artery disease. Lancet. 1992; 340:507-510.
4. Teitelbaum JE, et al. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. J Altern Complement Med. 2006 Nov;12(9):857-62.
5. Zimmer HG. Significance of the 5-phosphoribosyl-1-pyrophosphate pool for cardiac purine and pyrimidine nucleotide synthesis: studies with ribose, adenine, inosine, and orotic acid in rats. Cardiovasc Drugs Ther. 1998; 12 Suppl 2:179-187.
6. Zimmer HG. Regulation of and intervention into the oxidative pentose phosphate pathway and adenine nucleotide metabolism in the heart. Mol Cell Biochem. 1996; 160/161:101-109.